Pfeifer-Weber-Christian Disease during Pregnancy Successfully Treated with Corticosteroids

Sir, Pfeifer–Weber–Christian disease (PWCD), also known as idiopathic relapsing febrile lobular nonsuppurative panniculitis, is a rare inflammatory disorder of subcutaneous adipose tissue.[1] There is no specific test for diagnosis and extensive investigations are required to exclude systemic causes of panniculitis. No uniform effective therapy is available and various drugs have been used in the past.[2] It has been reported most frequently in people in the fourth to seventh decades of life, and 75% of cases occur in women after the second decade of life.[3] We present a case of PWCD during pregnancy successfully treated with corticosteroids. To the best of our knowledge, this is the first case of PWCD during pregnancy, described in the published literature.